Yanan Hao

Title: Yanan Hao - Innovator in L-Valine Production

Introduction

Yanan Hao is a prominent inventor based in Tianjin, China. He has made significant contributions to the field of biotechnology, particularly in the production of amino acids through fermentation processes. His innovative work has led to advancements that enhance the efficiency of L-valine production.

Latest Patents

Yanan Hao holds a patent for a genetically engineered strain with a high yield of L-valine and a method for producing L-valine by fermentation. This patent describes a genetically engineered strain derived from W3110, which incorporates several genetic modifications to optimize L-valine production. The strain features the insertion and overexpression of an acetolactate synthase gene, as well as the introduction of a mutant gene for ppGpp 3'-pyrophosphate hydrolase. Additionally, the method improves L-valine fermentation through a two-stage dissolved oxygen control, resulting in increased L-valine titer and enhanced sugar-acid conversion rates.

Career Highlights

Yanan Hao is affiliated with the Tianjin University of Science and Technology, where he conducts research and development in biotechnology. His work focuses on genetic engineering and fermentation technology, contributing to advancements in the production of valuable amino acids.

Collaborations

Yanan Hao collaborates with notable colleagues, including Xixian Xie and Heyun Wu, who contribute to his research efforts and innovations in the field.

Conclusion

Yanan Hao's contributions to the biotechnology sector, particularly in L-valine production, showcase his innovative spirit and dedication to advancing scientific knowledge. His patented methods and collaborations highlight the importance of teamwork in achieving significant breakthroughs in biotechnology.