Company Filing History:
Years Active: 2019-2021
Title: **Yan Fan: A Pioneer in Amylase Variant Innovations**
Introduction
Yan Fan, an innovative inventor based in Nanjing, China, has made significant contributions to the field of bioengineering. With a total of three patents to his name, he has been instrumental in developing novel amylase variants that have high catalytic activity and stability under extreme conditions. His work reflects a deep understanding of enzymatic processes, which are crucial for various industrial applications.
Latest Patents
Among Yan Fan's latest patents are two groundbreaking inventions. The first patent is for an **α-amylase variant and use thereof**. This invention outlines a variant obtained through the mutation or deletion of certain amino acid residues in the sequence of a parent α-amylase. Notably, this variant retains the capability to hydrolyze α-1,4 glycosidic bonds while achieving over 95% homology with the parent amino acid sequence. This series of α-amylase variants exhibits significant catalytic activity at an acidic pH of 5.0 and high temperatures exceeding 100°C.
The second patent is for an **L-type amylase variant and use thereof**. This invention introduces a variant of α-amylase that is modified by deleting the first N-terminal amino acid residue (V) and replacing it with three amino acids (DGL). This α-amylase variant demonstrates high catalytic activity in acidic conditions ranging from pH 5.0 to 5.8 and remains stable at temperatures of 100°C and higher. These characteristics make the variants particularly suitable for applications in starch liquefaction.
Career Highlights
Yan Fan is associated with Nanjing Bestzyme Bio-engineering Co., Ltd., where his research and inventions contribute to advancements in bioengineering technologies. His understanding of enzyme functionality and modification has placed him at the forefront of innovative research in this industry.
Collaborations
In his endeavors, Yan collaborates closely with colleagues, including Xiuzhen Du and Feng Li. Their collective expertise helps enhance the scope and impact of their research, fostering a collaborative environment that propels innovative solutions in bioengineering.
Conclusion
Yan Fan's dedication to the development of amylase variants marks a significant achievement in bioengineering. His innovative patents not only reflect his expertise but also pave the way for advancements in enzymatic applications across various industries. Through his work at Nanjing Bestzyme Bio-engineering Co., Ltd., he continues to set a benchmark for future innovations, demonstrating the profound impact of research and development in the field.