Company Filing History:
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Years Active: 2017
Title: The Innovative Contributions of Ya-Jen Chang
Introduction
Ya-Jen Chang is a notable inventor based in Brookline, MA (US). He has made significant contributions to the field of medical research, particularly in the treatment and prevention of inflammatory diseases. His work has implications for conditions such as asthma and autoimmune diseases, showcasing the potential of innovative therapies.
Latest Patents
Ya-Jen Chang holds a patent for "Methods for the treatment and prevention of inflammatory diseases." This patent demonstrates that treatment of young, suckling mice with a glycolipid derived from certain sources activates NKT cells in a CD1d-restricted fashion. This activation is protective against airway hyperreactivity in a model of allergen-induced asthma. The research further indicates that the protective effect can be transferred by NKT cells exposed to the glycolipid, which is associated with the expansion of suppressive double-negative NKT cells and Foxp3 T cells. Additionally, pre-treatment of adult mice with the glycolipid partially suppresses airway hyperreactivity and inhibits BAL inflammation in an ozone-exposure model. The patent provides compositions and methods for treating and preventing inflammatory diseases in subjects in need.
Career Highlights
Throughout his career, Ya-Jen Chang has worked with reputable organizations, including Children's Medical Center Corporation and the University of Birmingham. His research has been pivotal in advancing our understanding of inflammatory diseases and their treatments.
Collaborations
Ya-Jen Chang has collaborated with esteemed colleagues, including Dale T. Umetsu and Rosemarie H. De Kruyff. These collaborations have enriched his research and contributed to the development of innovative therapeutic approaches.
Conclusion
Ya-Jen Chang's contributions to the field of medical research, particularly in the treatment of inflammatory diseases, highlight the importance of innovation in healthcare. His patent and collaborative efforts reflect a commitment to improving patient outcomes through scientific advancement.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.