Xuedong Fan

Title: Xuedong Fan: Innovator in TNF-α Convertase Research

Introduction

Xuedong Fan is a prominent inventor based in Union, NJ (US). He has made significant contributions to the field of biochemistry, particularly in the area of TNF-α convertases. With a total of 5 patents to his name, his work has implications for medical treatments and therapeutic interventions.

Latest Patents

Xuedong Fan's latest patents focus on nucleic acids encoding human TNF-α convertase. The inventions provide isolated human and bovine TNF-α convertases, nucleic acids, and recombinant vectors encoding the same. Additionally, the patents describe host cells that comprise these nucleic acids and vectors, along with methods for producing the convertases using the host cells. The inventions also include antibodies and antigen-binding fragments that specifically bind to the convertases, which are useful for treating medical conditions caused or mediated by TNF-α. Furthermore, the patents outline screening methods for identifying specific inhibitors of mammalian TNF-α convertases and for identifying nucleic acids encoding such convertases.

Career Highlights

Xuedong Fan is currently associated with Schering Corporation, where he continues to advance his research and innovations. His work has been instrumental in developing new therapeutic strategies that target TNF-α convertases, which play a crucial role in various medical conditions.

Collaborations

Xuedong has collaborated with notable colleagues, including Barbara Dalie and Daniel Lundell. These collaborations have contributed to the advancement of research in the field of TNF-α convertases.

Conclusion

Xuedong Fan's innovative work in the field of TNF-α convertases has the potential to lead to significant advancements in medical treatments. His contributions are vital for understanding and addressing conditions mediated by TNF-α.