Location History:
- Duarte, CA (US) (2020 - 2023)
- Temple City, CA (US) (2023)
Company Filing History:
Years Active: 2020-2024
Title: Innovations and Contributions of Inventor Xiuli Wang
Introduction
Xiuli Wang is a prominent inventor based in Duarte, California, known for his significant contributions to the field of cancer therapy. With a total of five patents to his name, Wang has been at the forefront of developing innovative methods to enhance the efficacy of cancer treatments.
Latest Patents
One of Wang's latest patents focuses on the use of endogenous viral vaccines in chimeric antigen receptor (CAR) T cell therapy. This patent describes methods and compositions that include T cells expressing a recombinant CAR protein capable of specifically binding to cancer-specific antigens. Additionally, it incorporates a T cell receptor specific for a viral antigen, such as the CMV pp65 protein. The engineered T cells can be used in combination with a viral vaccine, like the cytomegalovirus (CMV) Triplex Vaccine, to treat various cancers. This method allows for in vivo expansion of CMV-specific CAR T cells, which helps avoid excessive T cell exhaustion that can occur from ex vivo manufacturing.
Another notable patent by Wang involves CS1 targeted chimeric antigen receptor-modified T cells for the treatment of AL amyloidosis. This patent outlines methods for treating AL amyloidosis using chimeric antigen receptors that specifically target CS1, showcasing Wang's commitment to addressing complex medical challenges.
Career Highlights
Throughout his career, Xiuli Wang has worked with esteemed organizations such as City of Hope and Baker Hughes, a GE Company, LLC. His work in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Wang has collaborated with notable colleagues, including Stephen J. Forman and Christine E. Brown. These partnerships have further enriched his research and development efforts in cancer therapies.
Conclusion
Xiuli Wang's innovative work in the field of cancer treatment through his patents and collaborations highlights his significant impact on medical science. His contributions continue to pave the way for advancements in therapeutic strategies against cancer.