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Title: Innovations and Contributions of Inventor Xin Chen
Introduction
Xin Chen is a prominent inventor based in Nanjing, China. He has made significant contributions to the field of biotechnology, particularly in the development of novel therapeutic agents and protein transfer technologies. With a total of 5 patents, his work has garnered attention for its potential applications in treating serious medical conditions.
Latest Patents
One of Xin Chen's latest patents is an "Aniline-based WDR5 protein-protein interaction inhibitor, and preparation method and use thereof." This patent discloses a WDR5 protein-protein interaction inhibitor that selectively inhibits the proliferation of leukemia cells. The inhibitor acts on WDR5 protein and its interacting proteins, including MLL, and has shown to inhibit the methylation of H3K4 and the expression of downstream Hox/Meis-1 gene at the cellular level. The patent also outlines a method for preparing the inhibitor and its use in developing drugs for treating acute leukemia and related diseases.
Another notable patent is the "Rapid blotting device and applications thereof." This invention provides a wet protein blotting system that includes a dry assembly module, a protein blotting chamber, a liquid transfer buffer handling system, and a control panel with power supply. The system significantly reduces the blotting time compared to traditional methods while maintaining high sensitivity in transferring proteins from polyacrylamide gels to membranes. The invention also features dry assembly modules and liquid transfer buffer handling systems that enable fully automatic buffer manipulation, enhancing transfer efficiency.
Career Highlights
Xin Chen has worked with notable organizations such as Nanjing Genscript Biotech Co., Ltd. and Nanjing University. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Throughout his career, Xin Chen has collaborated with talented individuals, including Chao Wang and Hong Qian, who is a woman. These collaborations have played a crucial role in advancing his research and innovations.
Conclusion
Xin Chen's contributions to biotechnology through his patents and collaborations highlight his role as an influential inventor. His work continues to pave the way for advancements in medical treatments and protein transfer technologies.