Company Filing History:
Years Active: 2025
Title: The Innovative Journey of Xiaoyang Fan: Advancements in Polypeptide Production
Introduction: Xiaoyang Fan, an inventive mind hailing from Nanjing, China, has made significant contributions to the field of genetic engineering and polypeptide preparation. With one registered patent, Fan's work represents a remarkable advancement in the efficient production of Semaglutide intermediate polypeptide.
Latest Patents: Fan's notable patent is for a fusion protein and its preparation method for the intermediate polypeptide of Semaglutide. This invention encompasses a fusion protein that integrates a fusion peptide, a protease cleavage site, and a target main molecular sequence. By optimizing the fusion peptide sequence and altering the isoelectric point and hydrophilicity of the protein, Fan has achieved an impressive enhancement in the expression of the fusion protein, reaching a maximum of 13.1 g/L. Furthermore, the resulting properties of the fusion protein enhance the processes of extraction, enzyme digestion, and purification, culminating in a yield of 3.62 g/L of the intermediate polypeptide post-digestion. This invention significantly reduces the production cost of the Semaglutide intermediate polypeptide Arg34GLP-1(9-37), facilitating industrial scale-up and suitability for large-scale production.
Career Highlights: Xiaoyang Fan is currently associated with Nanjing Hanxin Pharmaceutical Technology Co., Ltd., where he continues to drive innovation in pharmaceutical technologies. His expertise in polypeptide production not only reflects his dedication to advancing the field but also emphasizes the importance of cost-effective solutions in the pharmaceutical industry.
Collaborations: Throughout his career, Fan has collaborated with various professionals, including his coworker Jing Wang, to further enhance the research and development processes within Nanjing Hanxin Pharmaceutical Technology Co., Ltd. Their joint efforts exemplify the collaborative spirit necessary for scientific advancements in challenging fields like genetic engineering.
Conclusion: Xiaoyang Fan's contributions to the pharmaceutical industry, particularly through his innovative patent related to semaglutide intermediate polypeptide production, mark a significant step forward in the realm of genetic engineering and its practical applications. His work not only improves protein expression and production efficiency but also paves the way for advancements in industrial-scale pharmaceutical manufacturing.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.