Company Filing History:
Years Active: 2022-2025
Title: Innovations and Contributions of Xiaoyan Robert Bao
Introduction
Xiaoyan Robert Bao is a notable inventor based in Foster City, CA (US). He has made significant contributions to the field of genomic modification and T-cell engineering. With a total of 3 patents, his work focuses on improving the accuracy and effectiveness of therapeutic approaches in immunology.
Latest Patents
Bao's latest patents include innovative methods for performing GUIDE-Seq on primary human T cells. These methods are designed to identify the effects of genomic modifications, including off-target effects, with high accuracy. This is crucial for validating therapeutic T-cell engineering approaches. Another significant patent involves compositions and methods for identifying antigen-specific T cells. This patent introduces antigenic peptide-MHC complexes, known as comPACT polypeptides and comPACT polynucleotides. It also details methods for producing these complexes and libraries of comPACT polynucleotides and polypeptides, which are essential for capturing cancer neoepitope-reactive T cells with improved accuracy. Additionally, Bao's work includes dual particle detection approaches for detecting neoantigen-specific T cells, enhancing sensitivity and specificity.
Career Highlights
Throughout his career, Xiaoyan Robert Bao has worked with several companies, including Adoc Ssf, LLC and Pact Pharma, Inc. His expertise in the field has allowed him to contribute to groundbreaking research and development in T-cell therapies.
Collaborations
Bao has collaborated with notable colleagues, including Songming Peng and Boi Bryant Quach. These partnerships have furthered his research and innovation in the field of immunology.
Conclusion
Xiaoyan Robert Bao's contributions to the field of genomic modification and T-cell engineering are significant. His innovative patents and collaborations highlight his commitment to advancing therapeutic approaches in immunology. His work continues to impact the scientific community and improve patient outcomes.