Burlingame, CA, United States of America

Xiaoti Zhou


 

Average Co-Inventor Count = 4.9

ph-index = 3

Forward Citations = 26(Granted Patents)


Company Filing History:


Years Active: 2015-2016

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3 patents (USPTO):Explore Patents

Title: Innovative Contributions of Xiaoti Zhou in Pharmaceutical Patents

Introduction

Xiaoti Zhou, based in Burlingame, CA, has made significant strides in the field of pharmaceuticals through his innovative inventions. With a total of three patents to his name, Zhou's work exemplifies a commitment to scientific advancement and therapeutic development.

Latest Patents

Among his latest contributions are two key patents that focus on unique compounds with promising applications. The first patent outlines 4-hydroxy-isoquinoline compounds as HIF hydroxylase inhibitors. This invention highlights novel compounds capable of selectively inhibiting PHD1 enzyme activity over other isoforms, such as PHD2 and/or PHD3. The utility of these compounds extends to various disorders, including muscle degeneration, colitis, inflammatory bowel disease (IBD), and certain ischemic conditions.

The second patent addresses isothiazole-pyridine derivatives, which serve as modulators of HIF (hypoxia inducible factor) activity. This innovation presents novel compounds alongside methods and compositions designed to reduce HIF hydroxylase enzyme activity, thereby increasing the stability and effectiveness of hypoxia-inducible factor.

Career Highlights

Xiaoti Zhou is a valued employee at Fibrogen, Inc., a company known for its cutting-edge research and development in biopharmaceuticals. His work at Fibrogen has not only contributed to the company's success but has positioned him as an influential figure in his field.

Collaborations

During his career, Zhou has worked alongside esteemed colleagues such as Michael P Arend, fostering a collaborative environment that encourages innovation and further research. These partnerships are essential in driving forward the development of new therapeutic agents.

Conclusion

Xiaoti Zhou's contributions to the pharmaceutical industry through his innovative patents mark him as a noteworthy inventor. His ongoing work continues to bear the potential for significant therapeutic advancements, showcasing the importance of inventive minds in addressing complex medical challenges.

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