Company Filing History:
Years Active: 2004-2007
Title: Innovations by Inventor Xiaoning Bi: A Glimpse into His Patents and Contributions
Introduction: Xiaoning Bi is a prominent inventor based in Irvine, CA, renowned for his significant contributions to the field of neurodegenerative disease research. With a total of three patents under his name, he has made remarkable strides in understanding and developing treatments for conditions characterized by abnormal amyloid processing in the brain.
Latest Patents: Xiaoning Bi's latest patents focus on groundbreaking methods and compounds to tackle neurodegenerative diseases. One of his key inventions involves determining the effects of substances on the sequestration, uptake, and accumulation of amyloid in brain cells. This invention provides brain cells, including normal, apolipoprotein E deficient, and apoE4 containing brain cells, which have been treated with compounds that modulate integrins and integrin receptors. This results in increased sequestration and uptake of amyloid-beta, alongside changes in cathepsin D content and lysosomal dysfunction.
Furthermore, Bi has patented methods for treating neurodegenerative disorders using non-peptide aspartyl protease inhibitors. This invention outlines how to modulate the processing of amyloid precursor proteins and tau proteins, offering new avenues for the treatment of neurodegenerative diseases.
Career Highlights: Xiaoning Bi is affiliated with the University of California, where he has contributed extensively to research in neurodegenerative diseases. His innovative approaches have put him at the forefront of scientific inquiry in this critical field, pushing the boundaries of how we understand and potentially treat these conditions.
Collaborations: Throughout his career, Bi has worked alongside notable colleagues such as Gary S. Lynch and Jonathan A. Ellman. These collaborations have played a pivotal role in enhancing the quality and impact of his research, fostering a dynamic academic environment focused on neurological health.
Conclusion: Xiaoning Bi's work exemplifies the integral relationship between innovation and scientific advancement in the realm of neurodegenerative disease treatment. His patented inventions offer promising pathways for future research and therapeutic developments, highlighting his valuable contributions to the field and the potential benefits for those affected by these challenging conditions.