Old Tappan, NJ, United States of America

Xiaolin Tang

USPTO Granted Patents = 14 

 

 

Average Co-Inventor Count = 2.8

ph-index = 5

Forward Citations = 103(Granted Patents)


Company Filing History:


Years Active: 2015-2025

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14 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Inventor Xiaolin Tang

Introduction

Xiaolin Tang is a prominent inventor based in Old Tappan, NJ (US), known for his significant contributions to the field of pharmaceuticals. With a total of 14 patents to his name, he has made remarkable advancements in drug formulation and lyophilization methods.

Latest Patents

One of his latest patents focuses on achieving a target residual moisture content for lyophilized drug products. This patent outlines lyophilization methods for preparing protein formulations that can be stored long-term at room temperature or improved stability at refrigeration storage. Specifically, it provides methods to obtain a target percentage of residual moisture, such as 3-5%. The secondary drying process can be controlled under a temperature similar to the shelf temperature of the primary drying, or it can be conducted without a distinguished secondary drying step.

Another notable patent addresses the reduction of subvisible particles in pharmaceutical formulations. This disclosure presents a stable protein composition containing a surfactant, which has less than 400 subvisible particles of 10 microns or greater diameter per container, or less than 10,000 subvisible particles of 2 microns or greater per container. The method of manufacturing this stable protein composition includes a unit of operation that removes or decreases esterase activity that degrades the surfactant, utilizing techniques such as hydrophobic interaction chromatography or filtration.

Career Highlights

Xiaolin Tang has worked with notable companies in the pharmaceutical industry, including Regeneron Pharmaceuticals, Inc. His experience in these organizations has contributed to his expertise in drug formulation and development.

Collaborations

Throughout his career, Xiaolin has collaborated with esteemed colleagues, including Daniel B Dix and Mary Kleppe. These collaborations have further enhanced his innovative work in the pharmaceutical sector.

Conclusion

Xiaolin Tang's contributions to the field of pharmaceuticals through his patents and collaborations highlight his role as a leading inventor. His work continues to impact the development of stable drug formulations and innovative lyophilization methods.

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