This inventor holds 3 USPTO granted patents. Top assignee: Johns Hopkins University. Active years: 1997-2000.
Company Filing History:
Years Active: 1997-2000
Title: Innovations of Inventor Xiao-Jiang Li
Introduction
Xiao-Jiang Li is a prominent inventor based in Baltimore, MD (US). She has made significant contributions to the field of biomedical research, particularly in understanding Huntington's Disease and taste perception. With a total of 3 patents, her work has garnered attention for its potential impact on drug development and sensory biology.
Latest Patents
One of her latest patents is focused on huntingtin-associated protein-related assays. This invention involves proteins that specifically bind to huntingtin, the product of the Huntington's Disease locus (HD). These proteins are utilized in assays for screening drug candidates, with a stronger binding affinity observed for huntingtins from patients with Huntington's Disease. The strength of this binding correlates with the number of glutamine repeats in the huntingtin, which is associated with the timing of disease onset.
Another notable patent is related to an amiloride-sensitive sodium channel and a method for identifying substances. This discovery has localized an amiloride-sensitive sodium channel (ENAC) to the epithelium of the tongue, including taste tissue. This finding provides a method for identifying substances that stimulate or block salty taste in mammals, with alternative spliced forms also identified.
Career Highlights
Xiao-Jiang Li is affiliated with Johns Hopkins University, where she conducts her research. Her work has been instrumental in advancing our understanding of complex biological processes and their implications for health and disease.
Collaborations
She has collaborated with notable researchers such as Solomon H. Snyder and Seth Blackshaw, contributing to a rich environment of scientific inquiry and innovation.
Conclusion
Xiao-Jiang Li's contributions to science through her patents and research at Johns Hopkins University highlight her role as a leading inventor in the field of biomedical research. Her work continues to pave the way for advancements in understanding and treating diseases.