Company Filing History:
Years Active: 2017
Title: Xianzhi Mao: Innovator in Gene Modulation
Introduction
Xianzhi Mao is a prominent inventor based in Ambler, PA (US). He has made significant contributions to the field of gene modulation, particularly in the development of compounds and methods that target various checkpoint genes.
Latest Patents
Xianzhi Mao holds 1 patent for his invention titled "Compositions for inhibiting checkpoint gene expression and uses thereof." This patent focuses on compounds, compositions, and methods that are useful for modulating the expression of PD1, PDL1, IDO1, LAG3, TIM3, CTLA4, IDO2, CEACAM1, OX40, and/or OX40L mRNA or protein. The invention utilizes gene silencing compounds that consist of two or more single-stranded antisense oligonucleotides linked through their 5'-ends, allowing for the presence of two or more accessible 3'-ends.
Career Highlights
Xianzhi Mao is currently associated with Idera Pharmaceuticals, Inc., where he continues to advance his research in gene modulation. His work has the potential to impact therapeutic strategies in various diseases.
Collaborations
He has collaborated with notable colleagues such as Sudhir Agrawal and Wayne Jiang, contributing to a dynamic research environment.
Conclusion
Xianzhi Mao's innovative work in gene modulation exemplifies the importance of research in advancing medical science. His contributions are paving the way for new therapeutic approaches in the treatment of diseases.
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