Company Filing History:
Years Active: 2020-2024
Title: Innovations of Xiangyang Liu
Introduction
Xiangyang Liu is a prominent inventor based in Madison, WI (US). He has made significant contributions to the field of biosensors and synthetic biology. With a total of 2 patents, his work focuses on innovative methods for detecting chemical compounds and designing programmable inducible promoters.
Latest Patents
One of his latest patents is a sensor for cyanuric acid detection. This biosensor includes a host strain or cell-free system with two expression cassettes. The first expression cassette contains a constitutive promoter and a gene encoding an AtzR cyanuric acid-responsive transcription factor. The second expression cassette features a promoter regulated by the AtzR transcription factor and a gene encoding a reporter protein. In the presence of cyanuric acid, the AtzR transcription factor drives the expression of the reporter protein, enabling effective detection.
Another notable patent involves methods of designing programmable inducible promoters. This method identifies synthetic inducible promoters with specified induction and repression for DNA binding proteins. It includes an in vitro selection from a polynucleotide library and an in vivo selection to produce an induced promoter library. The result is an induction table that allows the selection of promoters with specific properties, along with biosensors containing these synthetic inducible promoters.
Career Highlights
Xiangyang Liu is associated with the Wisconsin Alumni Research Foundation, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in environmental monitoring and synthetic biology.
Collaborations
He collaborates with notable colleagues, including Srivatsan Raman and Aseem Zoe Ansari. Their combined expertise contributes to the success of their research projects and innovations.
Conclusion
Xiangyang Liu's contributions to biosensor technology and synthetic biology highlight his role as an influential inventor. His innovative patents and collaborations continue to pave the way for advancements in these fields.