Company Filing History:
Years Active: 2003-2009
Title: Wu-Po Ma: Innovator in Nucleic Acid Detection
Introduction
Wu-Po Ma is a distinguished inventor based in Madison, WI (US). He has made significant contributions to the field of molecular biology, particularly in the detection and modification of nucleic acids. With a total of 3 patents, his work has advanced the understanding and application of nucleic acid technologies.
Latest Patents
Wu-Po Ma's latest patents include innovative inventions that focus on endonuclease-substrate complexes. This invention provides novel cleavage agents for the cleavage and modification of nucleic acids. These agents are particularly useful for the detection and characterization of nucleic acid sequences and variations. In some embodiments, an endonuclease activity is utilized to cleave a target-dependent cleavage structure, indicating the presence of specific nucleic acid sequences or variations thereof. Another significant patent involves enzymes designed for the direct detection, characterization, and quantitation of nucleic acids, especially RNA. This invention offers enzymes that recognize specific nucleic acid cleavage structures formed on target RNA sequences, cleaving them in a site-specific manner to produce non-target cleavage products. Additionally, the invention provides enzymes with improved abilities to cleave a DNA member of a complex comprising DNA and RNA nucleic acid strands.
Career Highlights
Wu-Po Ma is currently associated with Third Wave Technologies, Inc., where he continues to innovate in the field of nucleic acid technologies. His work has been instrumental in developing tools that enhance the detection and analysis of genetic material.
Collaborations
Throughout his career, Wu-Po Ma has collaborated with notable colleagues, including Hatim T Allawi and Michael W Kaiser. These collaborations have further enriched his research and contributed to the advancement of nucleic acid technologies.
Conclusion
Wu-Po Ma's contributions to the field of molecular biology through his patents and collaborations highlight his role as a key innovator in nucleic acid detection and modification. His work continues to impact the scientific community and advance the understanding of genetic material.