The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2003
Filed:
Jan. 11, 2001
Wu-Po Ma, Madison, WI (US);
Victor I. Lyamichev, Madison, WI (US);
Michael W. Kaiser, Madison, WI (US);
Natalie E. Lyamicheva, Madison, WI (US);
Hatim Taysir Allawi, Madison, WI (US);
James J. Schaefer, Madison, WI (US);
Bruce P. Neri, Madison, WI (US);
Third Wave Technologies, Inc., Madison, WI (US);
Abstract
The present invention relates to novel enzymes designed for direct detection, characterization and quantitation of nucleic acids, particularly RNA. The present invention provides enzymes that recognize specific nucleic acid cleavage structures formed on a target RNA sequence and that cleave the nucleic acid cleavage structure in a site-specific manner to produce non-target cleavage products. The present invention provides enzymes having an improved ability to specifically cleave a DNA member of a complex comprising DNA and RNA nucleic acid strands.