Company Filing History:
Years Active: 1998-2025
Title: The Innovations of Wolfram Ruf
Introduction
Wolfram Ruf is a prominent inventor based in San Diego, California. He has made significant contributions to the field of anticoagulant therapies, holding a total of five patents. His work focuses on improving methods for evaluating therapeutic efficacy and assessing bleeding risks in patients.
Latest Patents
Wolfram Ruf's latest patents include innovative methods for evaluating anticoagulant therapeutic efficacy. These methods involve providing a blood sample, perfusing it over a surface coated with collagen or immobilized rTF, and measuring platelet aggregation and fibrin deposition. The therapeutic efficacy of the anticoagulant is assessed based on the volume of platelet aggregates and deposited fibrin. Another notable patent is for a thrombin generation assay, which measures thrombin generated in a blood sample. This assay includes incubating the blood sample with TF, FIXa, and CaCl2, and determining bleeding risks based on the amount of coagulation factor VIII in the sample.
Career Highlights
Wolfram Ruf is affiliated with The Scripps Research Institute, where he continues to advance research in his field. His work has been instrumental in developing new methodologies that enhance patient care and treatment outcomes.
Collaborations
Wolfram Ruf has collaborated with esteemed colleagues such as Thomas S. Edgington and Zaverio M. Ruggeri. These partnerships have fostered innovation and contributed to the advancement of research in anticoagulant therapies.
Conclusion
Wolfram Ruf's contributions to the field of anticoagulant therapies through his patents and collaborations highlight his role as a leading inventor. His work continues to impact the medical community positively.