Wolfgang Koehnlein

Title: Wolfgang Koehnlein: Innovator in PEGylated Protein Composition

Introduction

Wolfgang Koehnlein is a notable inventor based in Benediktbeuern, Germany. He has made significant contributions to the field of biochemistry, particularly in the development of PEGylated protein compositions. With a total of 3 patents, his work has advanced the understanding and application of protein modifications.

Latest Patents

Koehnlein's latest patents focus on processes for providing PEGylated protein compositions. One of his key innovations involves a method for creating a mixture of non-PEGylated, mono-PEGylated, and oligo-PEGylated proteins. This process is particularly effective for producing mono-PEGylated erythropoietin compositions. The method includes reacting a non-PEGylated protein with a PEGylation reagent, followed by anion exchange chromatography to separate the components. Additionally, he has developed a process that utilizes hydrophobic interaction chromatography to enhance the yield of mono-PEGylated protein compositions.

Career Highlights

Throughout his career, Koehnlein has worked with prominent companies in the pharmaceutical industry, including Hoffmann-La Roche Inc. and F. Hoffmann-La Roche AG. His experience in these organizations has allowed him to refine his expertise in protein engineering and biopharmaceutical development.

Collaborations

Koehnlein has collaborated with several professionals in his field, including Roberto Falkenstein and Wolfgang Kuhne. These partnerships have contributed to the advancement of his research and the successful implementation of his patented processes.

Conclusion

Wolfgang Koehnlein's innovative work in PEGylated protein compositions has made a significant impact in biochemistry. His patents and collaborations reflect his dedication to advancing the field and improving therapeutic applications.