The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2022
Filed:
Dec. 28, 2018
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventor:
Wolfgang Koehnlein, Penzberg, DE;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01D 15/08 (2006.01); A61K 47/60 (2017.01); C07K 1/20 (2006.01); C07K 14/00 (2006.01); C07K 14/505 (2006.01); C07K 16/00 (2006.01); B01D 15/16 (2006.01); B01D 15/18 (2006.01); B01D 15/32 (2006.01); C12N 9/96 (2006.01);
U.S. Cl.
CPC ...
C07K 1/20 (2013.01); A61K 47/60 (2017.08); B01D 15/166 (2013.01); B01D 15/1871 (2013.01); B01D 15/327 (2013.01); C07K 14/505 (2013.01); C12N 9/96 (2013.01);
Abstract
A process for providing a mono-PEGylated protein composition is provided. The process is particularly suitable for providing mono-PEGylated erythropoietin composition. The process comprises subjecting a mixture comprising non-PEGylated, mono-PEGylated and oligo-PEGylated to a hydrophobic interaction chromatography process.