Location History:
- Brisbane, AU (1990)
- Oakland, CA (US) (1984 - 1997)
- Balmoral Heights, AU (1988 - 1997)
Company Filing History:
Years Active: 1984-1997
Title: **Innovative Contributions of Wolfgang H Hanisch in Biopharmaceuticals**
Introduction
Wolfgang H Hanisch, an esteemed inventor based in Brisbane, Australia, has made significant contributions to the field of biopharmaceuticals. With a total of six patents to his name, he has developed innovative processes that enhance the recovery and formulation of lipophilic proteins, including human β-interferon, which has crucial therapeutic applications.
Latest Patents
Among his latest patents are two noteworthy inventions focused on lipophilic proteins. The first patent describes a process for recovering and purifying lipophilic recombinant proteins. This advanced method involves several steps: concentrating bacteria, disrupting cell walls, and solubilizing proteins into an aqueous medium using a suitable solubilizing agent. The extraction of the protein is performed using solvents such as 2-butanol and 2-methyl-2-butanol. The subsequent purification of the protein is achieved through chromatography and diafiltering, ensuring that therapeutic formulations maintain low levels of SDS, specifically less than 10 parts per million.
The second patent presents an innovative formulation process for creating highly stable pharmaceutical compositions of biologically active recombinant lipophilic proteins, such as human β-interferon and interleukin-2. These formulations are designed to remain effective when dissolved in a non-toxic, aqueous-based carrier at specific pH ranges, further enhanced by stabilizers including human serum albumin and dextrose. This advanced formulation method avoids harsh alkaline conditions, making it safer for therapeutic use.
Career Highlights
Wolfgang H Hanisch collaborates with Cetus Corporation, where he drives forward the advancement of biopharmaceutical technologies. His innovative approaches have positioned him as a key figure in the development of recombinant proteins, significantly improving therapeutic efficacy and stability.
Collaborations
Throughout his career, Hanisch has had the privilege of working alongside notable colleagues such as Peter M Fernandes and Glenn J Dorin. These collaborations have facilitated a rich exchange of ideas and accelerated advancements in their shared field of expertise.
Conclusion
Wolfgang H Hanisch's pioneering work in the recovery and formulation of lipophilic proteins marks a significant contribution to the biopharmaceutical industry. With his innovative patents and collaborations, he continues to shape the future of therapeutic applications, enhancing the efficacy and safety of biologically active proteins for medical use.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.