Location History:
- Eppstein, DE (2007 - 2009)
- Frankfurt-am-Main, DE (2021 - 2023)
Company Filing History:
Years Active: 2007-2023
Title: Innovations by Wolfgang Fiedler: Pioneering Methods in Peptide Synthesis
Introduction
Wolfgang Fiedler, an accomplished inventor based in Frankfurt am Main, Germany, has made significant contributions to the field of peptide synthesis. With a portfolio that includes four patents, Fiedler's innovations focus primarily on methods that enhance the efficiency and effectiveness of polypeptide synthesis.
Latest Patents
Fiedler's latest patents reveal advanced techniques that address critical challenges in peptide synthesis. One of his notable inventions is the "Method for cleavage of solid phase-bound peptides from the solid phase." This invention outlines a process where the solid phase-bound polypeptide is treated with a composition of trifluoroacetic acid and 1,2-ethanedithiol under controlled temperature conditions, specifically between 23°C and 29°C.
Another significant patent is titled "Capping of unprotected amino groups during peptide synthesis." This innovation pertains to a novel approach for synthesizing polypeptides with predetermined amino acid sequences. The method involves a systematic coupling process where protected amino acid building blocks are strategically added to an unprotected amino group, ensuring the integrity of the peptide chain through capping and de-protection steps.
Career Highlights
Wolfgang Fiedler is associated with Sanofi-Aventis Deutschland GmbH, where he actively engages in research and development within the pharmaceutical sector. His work is pivotal in advancing the synthesis techniques that are vital for drug development, aiding in the creation of more effective therapeutic agents.
Collaborations
In his innovative journey, Fiedler collaborates with esteemed colleagues Bernd Neises and Jochen Hachtel. Together, they contribute to the collective expertise within their organization, pushing the boundaries of research in the synthesis of complex polypeptides.
Conclusion
With a robust patent portfolio and a commitment to innovation, Wolfgang Fiedler stands as a prominent figure in the field of peptide synthesis. His cutting-edge methods not only enhance scientific understanding but also hold potential for significant applications in drug development, showcasing the impact of his contributions to the industry.