The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Apr. 10, 2019
Applicant:
Sanofi-aventis Deutschland Gmbh, Frankfurt am Main, DE;
Inventors:
Bernd Henkel, Frankfurt am Main, DE;
Tobias Metzenthin, Frankfurt am Main, DE;
Manfred Gerken, Frankfurt am Main, DE;
Wolfgang Fiedler, Frankfurt am Main, DE;
Assignee:
SANOFI-AVENTIS DEUTSCHLAND GMBH, Frankfurt Am Main, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/04 (2006.01); C07K 1/10 (2006.01); C07K 1/06 (2006.01); C07K 14/605 (2006.01);
U.S. Cl.
CPC ...
C07K 1/10 (2013.01); C07K 1/062 (2013.01); C07K 1/064 (2013.01); C07K 1/066 (2013.01); C07K 14/605 (2013.01);
Abstract
The present invention relates to a method for the synthesis of a polypeptide comprising a pre-determined amino acid sequence. The method according to the invention comprises coupling cycles of coupling an N-terminally protected amino acid building block C-terminally at an unprotected N-terminal amino group of an amino acid chain, wherein at least one coupling cycle comprises a coupling step (a), a capping step (b), and a de-protecting step (c).