Wk Alfred Yung

Title: Wk Alfred Yung: Innovator in Cancer Therapy

Introduction

Wk Alfred Yung is a prominent inventor based in Houston, TX, known for his significant contributions to cancer therapy. He holds two patents that focus on innovative approaches to treating cancer through the use of oncolytic viruses and immunomodulation.

Latest Patents

His latest patents include groundbreaking inventions such as biomarkers and combination therapies using oncolytic virus and immunomodulation. This invention describes biomarkers that are useful for prognosis, selection, and monitoring of oncolytic virus therapy for patients with various types of cancer. The present invention identifies proteins whose expression patterns are strongly predictive of the outcome of oncolytic virus therapy in cancer patients. It also provides a method for identifying and selecting cancer patients who are likely to be non-responsive to oncolytic virus therapy. These patients can be co-administered an agent that stimulates a cell-mediated immune response alongside the oncolytic virus or can receive alternative therapies. Another notable patent involves oncolytic adenovirus armed with therapeutic genes. This invention comprises compositions and methods for treating cancer using a mutant adenovirus that includes a polynucleotide encoding a therapeutic polypeptide targeted to cells with a mutant retinoblastoma pathway. The mutant adenovirus effectively kills tumor cells while sparing those with a wild type retinoblastoma pathway.

Career Highlights

Wk Alfred Yung has had a distinguished career, working with reputable organizations such as the University of Texas System and Dnatrix, Inc. His work has significantly advanced the field of cancer research and therapy.

Collaborations

Throughout his career, he has collaborated with notable colleagues, including Candelaria Gomez-Manzano and Charles A Conrad. These collaborations have further enriched his research and contributions to cancer treatment.

Conclusion

Wk Alfred Yung's innovative work in cancer therapy through oncolytic viruses and immunomodulation showcases his dedication to improving patient outcomes. His patents reflect a commitment to advancing medical science and providing new hope for cancer patients.