Location History:
- Watchung, NJ (US) (1993)
- Durham, NC (US) (1995)
Company Filing History:
Years Active: 1993-1995
Title: Innovations of Wilson B Knight
Introduction
Wilson B Knight is a notable inventor based in Watchung, NJ (US). He has made significant contributions to the field of medical research, particularly in the development of therapeutic agents for treating inflammatory and degenerative diseases. With a total of 3 patents, his work has had a meaningful impact on clinical practices.
Latest Patents
Knight's latest patents include an assay for evaluating the inhibition of polymorphonuclear leukocyte elastase. This invention focuses on N-substituted azetidinones, which are recognized as a class of inhibitors of human leukocyte elastase. These inhibitors are known to be beneficial in treating a variety of anti-inflammatory and antidegenerative diseases. The therapeutic agents form a stable complex with the enzyme, and the assay disclosed allows for the hydrolysis of this inhibitor-enzyme complex. Specific products of the hydrolysis can be measured, making the assays useful in clinical settings for determining appropriate dosages and assessing treatment effectiveness.
Career Highlights
Wilson B Knight is associated with Merck & Co., Inc., where he has been able to apply his innovative ideas in a collaborative environment. His work has contributed to advancements in medical treatments and has been recognized within the industry.
Collaborations
Some of his notable coworkers include William K Hagmann and William A Hanlon. Their collaboration has likely fostered an environment of innovation and shared expertise.
Conclusion
Wilson B Knight's contributions to the field of medical research through his patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of effective treatments for various diseases.