William Seth Horne

Title: Innovations of William Seth Horne

Introduction

William Seth Horne is a notable inventor based in Madison, WI (US). He has made significant contributions to the field of biotechnology, particularly in the development of biologically active peptides. With a total of 4 patents to his name, Horne's work has the potential to impact various applications in medicine and research.

Latest Patents

One of Horne's latest patents is a method of making biologically active alpha-beta peptides. This innovative method involves selecting a biologically active polypeptide or its fragment that contains alpha-amino acid residues. The process includes fabricating a synthetic polypeptide that mirrors the amino acid sequence of the original biologically active polypeptide. However, it replaces approximately 14% to 50% of the alpha-amino acid residues with beta-amino acid residues, arranged in a repeating pattern. This advancement opens new avenues for creating unnatural polypeptides with specific biological activities.

Career Highlights

Horne is associated with the Wisconsin Alumni Research Foundation, where he continues to explore and develop his innovative ideas. His work has garnered attention in the scientific community, contributing to advancements in peptide synthesis and applications.

Collaborations

Horne has collaborated with esteemed colleagues such as Samuel Helmer Gellman and Lisa M Johnson. These partnerships have fostered a collaborative environment that enhances the research and development of new biotechnological solutions.

Conclusion

William Seth Horne's contributions to the field of biotechnology through his innovative patents and collaborations highlight his role as a significant inventor. His work in developing biologically active peptides showcases the potential for advancements in medical and research applications.