Company Filing History:

12 out of 3,221

Genentech, Inc.

Years Active: 2005-2014

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15 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 8911735 - Complement inhibitors and uses thereof (2014-12-16),

2. 8907072 - Nucleic acids encoding antibody 137-26 which binds C5 and C5a (2014-12-09),

3. 8765131 - Methods of inhibiting alternative pathway complement activation with anti-factor D antibodies (2014-07-01),

4. 8383802 - Nucleic acids encoding antibodies that bind factor D (2013-02-26),

5. 8372404 - Anti-C5/C5a antibodies and methods of use (2013-02-12),

6. 8236317 - Methods of treating with anti-factor D antibodies (2012-08-07),

7. 8221756 - Complement inhibitors and uses thereof (2012-07-17),

8. 8206716 - Methods of treating with anti-C5/C5a specific antibodies (2012-06-26),

9. 8124090 - Anti-factor D antibodies and methods of treatment (2012-02-28),

10. 7943135 - Method of treatment using anti-factor D antibodies (2011-05-17),

11. 7439331 - Inhibition of complement activation (2008-10-21),

12. 7432356 - Complement pathway inhibitors binding to C5 and C5a without preventing formation of C5b (2008-10-07),

13. 7112327 - Inhibition of complement activation (2006-09-26),

14. 6998468 - Anti-C2/C2a inhibitors of complement activation (2006-02-14),

15. 6956107 - Inhibitors of complement activation (2005-10-18),

Title: Innovations of William N C Sun

Introduction

William N C Sun is a prominent inventor based in Bellaire, TX (US), known for his significant contributions to the field of biotechnology. He holds a total of 15 patents, showcasing his innovative spirit and dedication to advancing medical science.

Latest Patents

Among his latest patents, one notable invention is related to complement inhibitors and their uses. This invention focuses on C2a inhibitors, which bind to C2a and block its functional activity in complement activation. The inhibitors include various forms such as antibody molecules, homologs, analogs, and modified or derived forms, including immunoglobulin fragments like Fab, F(ab'), and Fv. Additionally, small molecules, peptides, oligonucleotides, peptidomimetics, and organic compounds are part of this invention. A specific monoclonal antibody, designated 175-62, was generated to bind to C2a and inhibit its ability to activate complement. The hybridoma producing this antibody has been deposited at the American Type Culture Collection under Accession Number PTA-1553.

Another significant patent involves nucleic acids encoding antibody 137-26, which binds to C5 and C5a. This invention relates to inhibitors that bind to C5 and C5a without preventing the activation of C5 or inhibiting the formation of C5b. The monoclonal antibody designated MAb137-26 is an example of such an inhibitor molecule, which binds to a shared epitope of human C5 and C5a. These inhibitors are valuable for treating diseases mediated by excessive production of C5a and can also be used for diagnostic detection of C5 or C5a levels.

Career Highlights

William N C Sun has worked with notable companies in the biotechnology sector, including Genentech, Inc. and Tanox, Inc. His experience in these organizations has contributed to his expertise and innovative capabilities in the field.

Collaborations

Throughout his career, William has collaborated with esteemed colleagues such as Cecily R Y Sun and Michael S C Fung. These collaborations have likely enhanced his research and development efforts.

Conclusion

William N C Sun's contributions to biotechnology through his patents and collaborations highlight his role as a leading inventor in the field. His work continues to impact medical science and innovation significantly.

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