The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2013
Filed:
May. 29, 2012
Michael Fung, Gaithersburg, MD (US);
Meisheng LU, Houston, TX (US);
William N. C. Sun, Shanghai, CN;
Cecily R. Y. Sun, Shanghai, CN;
Michael Fung, Gaithersburg, MD (US);
Meisheng Lu, Houston, TX (US);
William N. C. Sun, Shanghai, CN;
Cecily R. Y. Sun, Shanghai, CN;
Genentech, Inc., South San Francisco, CA (US);
Abstract
The invention relates to inhibitors that bind to C5 and C5a, but which do not prevent the activation of C5 and do not prevent formation of or inhibit the activity of C5b. One example of such an inhibitor molecule is the monoclonal antibody designated MAb137-26, which binds to a shared epitope of human C5 and C5a. These inhibitors may be used to inhibit the activity of C5a in treating diseases and conditions mediated by excessive or uncontrolled production of C5a. The inhibitor molecules are also useful for diagnostic detection of the presence/absence or amount of C5 or C5a.