Cecily R Y Sun

Title: **Cecily R Y Sun: Innovator in Complement Inhibitors**

Introduction

Cecily R Y Sun, based in Bellaire, Texas, is a prominent inventor with an impressive portfolio of 24 patents. Her innovative work primarily revolves around complement inhibitors, contributing significantly to advancements in therapeutic applications.

Latest Patents

Among her latest inventions are novel complement inhibitors that specifically target and bind to the C2a component, blocking its functional activity in complement activation. These inhibitors comprise various antibody molecules, including their homologs, analogs, and modified forms, such as immunoglobulin fragments like Fab, F(ab')2, and Fv. Notably, she developed a monoclonal antibody, designated 175-62, which effectively binds to C2a, preventing it from activating the complement system. This crucial hybridoma is stored at the American Type Culture Collection under Accession Number PTA-1553.

Another pivotal patent involves nucleic acids encoding the antibody 137-26, which binds to C5 and C5a without inhibiting the activation of C5 or the formation of C5b. The monoclonal antibody MAb137-26 targets a shared epitope of human C5 and C5a and has potential applications in inhibiting the activity of C5a, which plays a role in diseases characterized by an excess of C5a production. These molecules are also instrumental for diagnostic purposes in detecting C5 or C5a levels.

Career Highlights

Cecily's career has seen her collaborate with leading companies in the biotechnology sector, particularly Genentech, Inc. Her contributions are not only limited to inventions but extend into practical biomedical applications that address critical health challenges.

Collaborations

Throughout her professional journey, Cecily has worked alongside notable colleagues, including William N C Sun and Michael S C Fung. Their collaborations have collectively furthered research and development in the field of complement inhibitors, emphasizing a strong teamwork dynamic in generating innovative solutions.

Conclusion

Cecily R Y Sun stands out as a groundbreaking inventor with significant contributions to the field of biomedical science. Her latest patents illustrate a focus on complement inhibitors that could revolutionize treatment methodologies, showcasing her role as a key player in the advancement of innovative therapeutic strategies. With a robust background and collaborative efforts, Cecily continues to lead in her quest for discoveries that enhance human health.