Location History:
- Redwood City, CA (US) (2021 - 2023)
- Stanford, CA (US) (2023)
- Menlo Park, CA (US) (2009 - 2024)
Company Filing History:
16 out of 5,307 
5 out of 123 
1 out of 18 Years Active: 2009-2025
Title: The Innovations of William J. Greenleaf: Advancements in DNA Analysis
Introduction: William J. Greenleaf, based in Menlo Park, California, is a prominent inventor with an impressive portfolio of 20 patents. His work primarily focuses on methods and compositions for analyzing DNA, which have pivotal implications for cancer research and diagnostics. Greenleaf's innovative approaches are at the forefront of genomic analysis, offering novel solutions in the life sciences.
Latest Patents: Among his latest contributions to the field, Greenleaf has developed compositions and methods for analyzing DNA using partitioning and base conversion techniques. This patent addresses the analysis of cell-free DNA, crucial for understanding conditions like cancer. It provides methodologies for partitioning DNA into subsamples, allowing distinct analyses of nucleotide modifications that could indicate the presence of cancer cells. Another significant patent involves methods for high-throughput single cell genomic and phenotypic analyses, utilizing double emulsion micro-droplets and flow cytometry for enhanced measurement efficiency and accuracy.
Career Highlights: Greenleaf has held notable positions at leading research institutions, including Leland Stanford Junior University, where he conducted extensive research in genomics. He later contributed to advancements at Guardant Health, Inc., a company known for its innovation in cancer detection through blood tests.
Collaborations: Throughout his career, Greenleaf has collaborated with influential colleagues such as Jason D. Buenrostro and Howard Y. Chang. These partnerships have facilitated groundbreaking research and innovation in the field of genomics, further enhancing the capabilities for individual patient analysis and treatment strategies.
Conclusion: William J. Greenleaf remains a key figure in the realm of DNA analysis innovations. His contributions through various patents not only push the boundaries of genomic research but also provide vital tools for early cancer detection and personalizing treatment. As the field evolves, Greenleaf’s work will undoubtedly continue to shape the future of medical diagnostics and patient care.