William G Kaelin

Boston, MA, United States of America

William G Kaelin

Nobel Prize
USPTO Granted Patents = 16 


Average Co-Inventor Count = 2.4

ph-index = 3

Forward Citations = 67(Granted Patents)


Company Filing History:


Years Active: 1998-2022

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16 patents (USPTO):Explore Patents

Title: William G. Kaelin: Innovator in Cancer Research and Therapeutics

Introduction: William G. Kaelin, based in Boston, MA, is a prominent figure in the field of cancer research and therapeutic innovation. With an impressive portfolio of 16 patents, he has made significant contributions to the understanding and treatment of various medical conditions, particularly focusing on hypoxia and protein dynamics.

Latest Patents: Kaelin's recent patents include "Methods and compositions for the positive selection of protein destabilizers." This innovation relates to the development of an assay that utilizes cell survival and viability as phenotypic identifiers to select agents that destabilize specific proteins of interest. Another noteworthy patent is titled "Pharmaceuticals and methods for treating hypoxia and screening methods therefor." This patent discloses light-generating fusion proteins that can serve as diagnostics and therapeutics, particularly under hypoxic conditions, taking advantage of ligand binding to activate bioluminescence for targeted therapeutic applications.

Career Highlights: William G. Kaelin has established a remarkable career, holding positions at esteemed institutions such as the Dana-Farber Cancer Institute and Alnylam Pharmaceuticals. His work in these organizations has contributed to groundbreaking advancements in cancer treatment methodologies and therapeutic innovation.

Collaborations: Throughout his career, Kaelin has collaborated with other distinguished researchers, including Mircea Ivan and David M. Livingston. These partnerships have amplified the impact of his research and fostered innovations within the scientific community.

Conclusion: William G. Kaelin's contributions to cancer research through his innovative patents and collaborative efforts with other leading scientists exemplify the critical role inventors play in advancing medical science. His work not only enhances our understanding of cancer mechanisms but also paves the way for new therapeutic approaches to treat complex medical conditions.

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