The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2022
Filed:
Sep. 13, 2017
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
William G. Kaelin, Boston, MA (US);
Vidyasagar Koduri, Brookline, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12Q 1/37 (2006.01); C12Q 1/48 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); C12N 9/12 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
G01N 33/502 (2013.01); C07K 14/00 (2013.01); C07K 14/435 (2013.01); C12N 9/1211 (2013.01); C12N 9/1229 (2013.01); C12N 9/1241 (2013.01); C12N 9/6472 (2013.01); C12Q 1/37 (2013.01); C12Q 1/485 (2013.01); C07K 2319/95 (2013.01); G01N 2500/10 (2013.01); G01N 2510/00 (2013.01);
Abstract
The present application relates, in some aspects, to the development of an assay that uses cell survival and/or cell viability as a phenotypic identifier to positively select for agents that destabilize a protein of interest.