This inventor holds 1 USPTO granted patent and 1 EPO patent. Top assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, The University of Edinburgh. Active years: 2015.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
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Years Active: 2015
Title: William C Earnshaw: Innovator in Synthetic DNA Technology
Introduction
William C Earnshaw is a prominent inventor based in Cingletie Peeples, GB. He is known for his significant contributions to the field of synthetic DNA technology, particularly in the formation of mammalian artificial chromosomes. His innovative methods have paved the way for advancements in genetic engineering and biotechnology.
Latest Patents
Earnshaw holds a patent titled "Rapid generation of long synthetic centromeric tandem repeats for mammalian artificial chromosome formation." This patent describes methods for constructing long synthetic arrays of DNA repeats, such as alphoid repeats or other repeat sequences. The techniques involve concatamerization of DNA into short repeats, utilizing methods like rolling circle amplification or directional in vitro ligation. These short repeats are then assembled into long arrays through homologous recombination during transformation into microbial cells. This process is generally referred to as Recombinational Amplification of Repeats (RAR). The engineered long arrays serve as centromere-like regions, enabling the construction of mammalian artificial chromosomes with a predefined centromeric region structure. The patent also covers artificial chromosomes, including human artificial chromosomes with a regulated centromere, along with methods for their use.
Career Highlights
Throughout his career, Earnshaw has worked with notable organizations, including the United States of America, as represented by the Secretary, Department of Health and Human Services, and the University of Edinburgh. His work has significantly impacted the field of genetic research and artificial chromosome development.
Collaborations
Earnshaw has collaborated with esteemed colleagues such as Vladimir L Larionov and Reto Gassman. These partnerships have contributed to the advancement of his research and the successful implementation of his innovative methods.
Conclusion
William C Earnshaw's contributions to synthetic DNA technology and artificial chromosome formation have established him as a key figure in the field. His innovative methods and collaborations continue to influence genetic research and biotechnology advancements.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile