Somerset West, South Africa

Willem Jacobus Perold

USPTO Granted Patents = 3 

 

Average Co-Inventor Count = 4.0

ph-index = 1


Location History:

  • Somerset West, ZA (2019 - 2020)
  • Stellenbosch, ZA (2023)

Company Filing History:


Years Active: 2019-2023

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3 patents (USPTO):Explore Patents

Title: Innovations by Inventor Willem Jacobus Perold

Introduction

Willem Jacobus Perold is a distinguished inventor based in Somerset West, South Africa. His work has led to numerous contributions in the field of medical technology, evident through his three registered patents. Perold’s inventions focus on critical health diagnostics, targeting various diseases and conditions.

Latest Patents

One of Perold's latest innovations is a patented method and device for determining autophagic flux. This patent provides a sophisticated approach to measuring the levels of proteins that fluctuate with changes in autophagy. By quantifying these variations, it becomes possible to assess autophagic flux and compare it with established ranges linked to autophagy dysfunction or age-related patterns. The device includes a housing designed to receive both a substrate and a biological sample, with integrated electrodes that assess the electrical properties necessary for determining autophagic flux. This patented technology is particularly relevant for diagnosing neurodegenerative conditions such as Alzheimer’s disease, cancer, heart-related issues, and various age-related disorders.

Another notable patent involves systems and methods for the detection of biomolecules. This innovation employs a unique system that utilizes piezoelectric signals obtained from a series of elongate zinc oxide nanowires. These nanowires, which are arranged parallel on a semi-conductive silicon substrate, interact with biomolecules capable of binding to complementary counterparts in biological or water samples. Through a careful incubation process, any molecular associations induce a displacement of the nanowires, leading to the generation of a piezoelectric voltage signal. This diagnostic capability is instrumental in identifying pathogenic infections and sample contaminations.

Career Highlights

Willem Jacobus Perold is associated with Stellenbosch University, where he continues his research and innovation endeavors. His academic background and ongoing commitment to scientific advancement have positioned him as a significant figure in his field.

Collaborations

Throughout his career, Perold has collaborated with notable colleagues such as Leon Milner, Theodore Dicks, and Benjamin Loos. These partnerships have fostered a creative environment conducive to groundbreaking discoveries in medical diagnostics.

Conclusion

Willem Jacobus Perold exemplifies the spirit of innovation through his significant contributions to medical technology. His patents highlight the transformative potential of science in addressing pressing health challenges. As he continues to develop and refine his inventions, Perold's work is poised to enhance diagnostic capabilities and ultimately improve patient outcomes.

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