The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2020

Filed:

Nov. 03, 2014
Applicant:

Stellenbosch University, Stellenbosch, ZA;

Inventors:

Leon Milner Theodore Dicks, Stellenbosch, ZA;

Willem Jacobus Perold, Somerset West, ZA;

Deon Nevwling, Stellenbosch, ZA;

Thomas Stanley Van Den Heever, Somerset West, ZA;

Assignee:

Stellenbosch University, Stellenbosch, ZA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/551 (2006.01); A61B 5/1473 (2006.01); A61B 5/00 (2006.01); G01N 15/10 (2006.01); G01N 33/553 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5438 (2013.01); A61B 5/14735 (2013.01); A61B 5/6861 (2013.01); G01N 15/1056 (2013.01); G01N 33/54373 (2013.01); G01N 33/551 (2013.01); G01N 33/553 (2013.01); A61B 2562/0285 (2013.01); G01N 2015/1062 (2013.01);
Abstract

A system and method for the detection and quantification of biomolecules by measuring a piezoelectric signal is described. The system comprises a plurality of elongate zinc oxide nanowires mounted generally parallel to each another on a semi conductive silicon substrate. The free ends of the nanowires are provided with biomolecules that are capable of associating with complementary biomolecules within a biological or water sample. Following incubation of the system in a sample, the association of molecules of interest with the immobilised biomolecules on the system results in the displacement of the zinc oxide nanowires. The displacement of the nanowires produces a piezoelectric voltage signal that is useful in diagnosing a pathogenic infection or the contamination of a sample.


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