Company Filing History:
Years Active: 2006-2024
Title: Werner Mueller: Innovator in Immunoglobulin Diversity
Introduction
Werner Mueller is a prominent inventor based in Cologne, Germany. He has made significant contributions to the field of immunology, particularly in enhancing immunoglobulin diversity. With a total of 4 patents, his work has paved the way for advancements in antibody production and genetic engineering.
Latest Patents
Mueller's latest patents include groundbreaking inventions such as "Long germline DH genes and long HCDR3 antibodies." This invention relates to a long DH (LDH) cassette comprising a recombinant DH construct that includes at least two DH gene segments encoding a minimum of 10 amino acids of the HCDR3 amino acid sequence. Notably, at least one of the DH gene segments is a heterologous DH gene segment. This innovation also encompasses an immunoglobulin heavy chain locus and a transgenic non-human animal, which can be utilized in producing an immunoglobulin library with long HCDR3 regions. Another significant patent is "Enhanced immunoglobulin diversity," which provides compositions and methods for the enhanced production of immunoglobulin diversity. This invention allows for the accessibility of a B cell receptor repertoire that has not been culled by developmental tolerance mechanisms, resulting in transgenic animals, cells, and antibodies derived from these compositions and methods.
Career Highlights
Throughout his career, Werner Mueller has worked with notable companies such as Trianni, Inc. and Miltenyi Biotec GmbH. His expertise in immunology and genetic engineering has been instrumental in the development of innovative solutions in these organizations.
Collaborations
Some of his notable coworkers include Matthias Wabl and Bao Duong, who have collaborated with him on various projects in the field of immunology.
Conclusion
Werner Mueller's contributions to immunoglobulin diversity and antibody production have established him as a key figure in the field of immunology. His innovative patents and collaborations continue to influence advancements in genetic engineering and immunological research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.