Wen-Bin Chung

Title: Innovations of Wen-Bin Chung

Introduction

Wen-Bin Chung is a notable inventor based in Neipu, Taiwan. He has made significant contributions to the field of biotechnology, particularly in the development of vaccines and immune response evaluation methods. With a total of 3 patents, his work has the potential to impact both veterinary medicine and immunology.

Latest Patents

Wen-Bin Chung's latest patents include a recombinant antigen and method of making the same, as well as an isolated polynucleotide of porcine reproductive and respiratory syndrome virus (PRRSV) and an immunogenic composition that includes the same. The recombinant antigen is a chimeric protein composed of PRRSV dual structural proteins and T-cell epitopes. This innovation allows for the mass production and purification of the recombinant protein expressed in a eukaryotic expression system. Additionally, the immunogenic composition can promote pro-inflammatory M1-phenotype polarization of porcine alveolar macrophages (PAMs), reduce receptor CD163 expression, and activate T helper (Th1) immune responses, making it applicable as a vaccine against PRRSV.

Another significant patent involves an in vitro immune synapse system and a method for evaluating immune responses. This system includes antigen-presenting cells (APCs) and various specific T cell subtypes isolated from peripheral blood mononuclear cells (PBMCs) of the same individual pigs. By co-culturing a test sample in this system, researchers can determine its immunogenicity and immunostimulatory properties, potentially reducing the need for certain animal experiments.

Career Highlights

Wen-Bin Chung is affiliated with the National Pingtung University of Science and Technology, where he continues to advance research in immunology and vaccine development. His innovative approaches have garnered attention in the scientific community, contributing to advancements in veterinary health.

Collaborations

Wen-Bin Chung collaborates with esteemed colleagues, including Hso-Chi Chaung and Mei-Li Wu, who contribute to his research endeavors. Their combined expertise enhances the quality and impact of their work.

Conclusion

Wen-Bin Chung's contributions to biotechnology and immunology through his patents and research at the National Pingtung University of Science and Technology highlight his role as an influential inventor in the field. His work promises to advance vaccine development and improve immune response evaluation