Hazelwood Park, Australia

Wei Ping Gai


Average Co-Inventor Count = 4.0

ph-index = 1

Forward Citations = 14(Granted Patents)


Company Filing History:


Years Active: 2007

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1 patent (USPTO):Explore Patents

Title: Innovations of Wei Ping Gai in Lewy Body Disease Research

Introduction

Wei Ping Gai is an accomplished inventor based in Hazelwood Park, Australia. He has made significant contributions to the field of neurodegenerative diseases, particularly in understanding Lewy Body Disease (LBD). His innovative work has led to the identification of novel fragments of alpha-synuclein, which play a crucial role in the pathology of LBD.

Latest Patents

Wei Ping Gai holds a patent titled "Truncated fragments of alpha-synuclein in Lewy body disease." This patent identifies fragments of alpha-synuclein in patients with LBD and transgenic animal models. The research highlights that these diseases are characterized by aggregations of alpha-synuclein. The identified fragments have a truncated C-terminus relative to full-length alpha-synuclein. Some fragments are characterized by a molecular weight of about 12 kDa, as determined by SDS gel electrophoresis in tricine buffer, and a truncation of at least ten contiguous amino acids from the C-terminus of natural alpha-synuclein. The site of cleavage preferably occurs after residue 117 and before residue 126 of natural alpha-synuclein. The identification of these novel fragments has numerous applications in drug discovery, diagnostics, therapeutics, and transgenic animals.

Career Highlights

Throughout his career, Wei Ping Gai has worked with notable organizations, including Elan Pharmaceuticals, Inc. and The Trustees of Flinders University. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Wei Ping Gai has collaborated with talented individuals such as Tamie Chilcote and Jason Marc Goldstein. These partnerships have further enhanced his research and innovation in the study of Lewy Body Disease.

Conclusion

Wei Ping Gai's contributions to the understanding of Lewy Body Disease through his innovative research and patent on alpha-synuclein fragments have significant implications for future therapeutic developments. His work continues to pave the way for advancements in the field of neurodegenerative diseases.

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