Company Filing History:
Years Active: 1999-2003
Title: Wei Gu: Innovator in Weight Modulation Research
Introduction
Wei Gu is a prominent inventor based in Brookline, MA (US), known for his significant contributions to the field of weight modulation. With a total of 6 patents, he has focused on developing innovative solutions for body weight disorders, including obesity and cachexia.
Latest Patents
Wei Gu's latest patents include groundbreaking work on GPR10 as a target for identifying weight modulating compounds. This invention discloses assays for identifying compounds that can modulate body weight, metabolic rate, or feeding behavior. These compounds are particularly useful in treating body weight disorders. The methods involve both cell-free and cell-based assays that identify compounds altering ligand binding to GPR10, a G protein-coupled receptor. Additionally, he has developed screening methods for compounds useful in regulating body weight, utilizing the melanocortin 4-receptor (MC4-R) as a target for intervention. This invention also relates to compounds that modulate the activity or expression of the MC4-R, aiding in the treatment of body weight disorders.
Career Highlights
Wei Gu has made significant strides in his career, particularly through his work at Millennium Pharmaceuticals Limited. His research has been pivotal in advancing the understanding of metabolic disorders and developing therapeutic interventions.
Collaborations
Wei Gu has collaborated with notable colleagues, including Frank Lee and Dennis Huszar, to further enhance the impact of his research in the field of weight modulation.
Conclusion
Wei Gu's innovative work and patents have made a substantial impact on the treatment of body weight disorders. His contributions continue to pave the way for future advancements in this critical area of health research.