The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2003
Filed:
Mar. 06, 2001
Applicant:
Inventors:
Alain Stricker-Kongra, Watertown, MA (US);
Wei Gu, Brookline, MA (US);
Assignee:
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/353 ; G01N 3/3566 ; G01N 3/3567 ; C12N 5/22 ; C12N 5/18 ;
U.S. Cl.
CPC ...
G01N 3/353 ; G01N 3/3566 ; G01N 3/3567 ; C12N 5/22 ; C12N 5/18 ;
Abstract
Assays for the identification of compounds useful for the modulation of body weight, metabolic rate, or feeding behavior are disclosed. Such compounds are useful for the treatment body weight disorders, e.g., obesity and cachexia. The methods involve cell-free and cell-based assays that identify compounds which alter ligand binding to and/or alter the activity of GPR10, a G protein-coupled receptor, optionally followed by an in vivo assay of the effect of the compound on feeding behavior, body weight, or metabolic rate.