Company Filing History:
Years Active: 1999
Title: The Innovations of Warren Kroeker
Introduction
Warren Kroeker is an accomplished inventor based in Madison, WI (US). He has made significant contributions to the field of biotechnology, particularly in the development of recombinant proteins. His innovative work has led to the creation of a patented product that has potential applications in various medical fields.
Latest Patents
Warren Kroeker holds a patent for the invention titled "Recombinant Rabbit Tissue Factor." This invention involves cloning and producing rabbit tissue factor in a bacterial host. The protein is relatively insoluble and contains several disulfide bonds, necessitating special modifications for commercial expression and purification. By expressing the tissue factor as a fusion protein with the bacterial enzyme thioredoxin, the solubility of the protein is enhanced. Additionally, using a thioredoxin reductase deficient host aids in achieving the proper tertiary structure necessary for biological activity. This patent showcases his expertise in protein engineering and biotechnology.
Career Highlights
Kroeker's career has been marked by his dedication to advancing biotechnological solutions. He works at Pel-Freez, a company known for its innovative approaches in the life sciences sector. His role at Pel-Freez allows him to apply his knowledge and skills in a practical setting, contributing to the development of cutting-edge biotechnological products.
Collaborations
Throughout his career, Warren Kroeker has collaborated with notable colleagues, including Robert E. Novy and Michael J. Domanico. These collaborations have fostered a productive environment for innovation and have led to advancements in their respective fields.
Conclusion
Warren Kroeker's contributions to biotechnology, particularly through his patent on recombinant rabbit tissue factor, highlight his role as a significant inventor in the industry. His work continues to influence the development of biotechnological solutions that can have a lasting impact on medical science.