Company Filing History:
4 out of 1,274 
1 out of 504 
1 out of 52 Years Active: 2009-2021
Title: Wanda Kay O'Neal: Innovator in Lung Disease Treatment
Introduction
Wanda Kay O'Neal is a prominent inventor based in Cary, North Carolina, known for her significant contributions to the field of lung disease treatment. With a total of four patents to her name, O'Neal has focused her research on innovative therapies aimed at alleviating conditions such as cystic fibrosis and chronic obstructive pulmonary disease.
Latest Patents
O'Neal's latest patents include groundbreaking work on the use of MTAP inhibitors for the treatment of lung disease. This invention relates to the application of 5'-methylthioadenosine phosphorylase (MTAP) inhibitors, which can help reduce inflammation associated with lung diseases. By sustaining the accumulation of endogenous MTA to therapeutically beneficial levels, these inhibitors show promise in decreasing inflammation in patients with cystic fibrosis and COPD. Another notable patent describes an animal model for chronic obstructive pulmonary disease and cystic fibrosis. This model features a nonhuman transgenic mammal with a genome that includes a promoter construct linked to a heterologous DNA encoding an epithelial sodium channel β subunit. This transgenic mammal exhibits increased lung mucus retention compared to its wild-type counterpart, making it a valuable tool for screening compounds aimed at treating lung diseases.
Career Highlights
Throughout her career, O'Neal has worked with esteemed institutions such as the University of North Carolina at Chapel Hill and Albert Einstein College of Medicine. Her research has significantly advanced the understanding and treatment of lung diseases, showcasing her dedication to improving patient outcomes.
Collaborations
O'Neal has collaborated with notable colleagues, including Richard C. Boucher and Barbara Grubb, further enhancing her research efforts and contributions to the field.
Conclusion
Wanda Kay O'Neal's innovative work in the treatment of lung diseases highlights her role as a leading inventor in the medical field. Her patents and research continue to pave the way for new therapeutic approaches, ultimately benefiting patients suffering from chronic lung conditions.