Company Filing History:
Years Active: 2012-2014
Title: Innovations by Wan-Jou Lee in Breast Cancer Detection
Introduction
Wan-Jou Lee is a prominent inventor based in Taipei, Taiwan. He has made significant contributions to the field of medical imaging, particularly in the detection and monitoring of breast cancer. With a total of 3 patents, his work focuses on developing algorithms that enhance the accuracy and effectiveness of infrared imaging techniques.
Latest Patents
One of Wan-Jou Lee's latest patents is the "Longitudinal image registration algorithm for infrared images for chemotherapy response monitoring and early detection of breast cancers." This innovative algorithm provides a marker-free approach to establishing pixel correspondence among infrared images taken at different times. It quantitatively characterizes the variation of heat energy and patterns on a breast surface. The algorithm utilizes corner points of heat patterns and branch points of skeletons on the body surface as initial fiducial points for longitudinal infrared image registration. The Thin-Plate Spline technique models the nonlinear deformation between two infrared images taken at different times. To optimize the registration, the Nelder-Mead simplex method is employed to maximize mutual information between the transformed image and the target image.
Another significant patent is the "Dual-spectrum heat pattern separation algorithm for assessing chemotherapy treatment response and early detection." This algorithm quantifies energy from high-temperature tissues, referred to as qmap, and decomposes the body surface into high and normal temperature areas based on middle-wave and long-wave infrared images. With longitudinal registration, it can detect cancerous tissues and assess chemotherapy treatment response on a pixel-by-pixel basis. Preliminary results indicate that the area and q-values in high-temperature areas decrease as patients undergo more chemotherapy, suggesting the algorithm's potential for effective chemotherapy assessment and early detection.
Career Highlights
Wan-Jou Lee is affiliated with National Taiwan University, where he continues to advance research in medical imaging technologies. His work has garnered attention for its innovative approach to cancer detection and treatment monitoring.
Collaborations
Wan-Jou Lee collaborates with notable colleagues, including Chung-Ming Chen and Si-Chen Lee, to further enhance the impact of his research in the medical field.
Conclusion
Wan-Jou Lee's contributions to the field of medical imaging, particularly in breast cancer detection, highlight the importance of innovation in healthcare. His patents reflect a commitment to improving patient outcomes through advanced technology.