Wai Yee Chan

Title: Innovations by Wai Yee Chan

Introduction

Wai Yee Chan is a prominent inventor based in Ma On Shan, China. She has made significant contributions to the field of biotechnology, particularly in the area of cellular reprogramming. With a total of 2 patents, her work focuses on innovative methods to induce pluripotency in differentiated mammalian cells.

Latest Patents

Wai Yee Chan's latest patents include groundbreaking inventions that utilize mechanical manipulation and programin derivatives. The first patent describes the combinational use of these techniques to increase the expression of Oct4, Sox2, Nanog, or c-Myc in fibroblasts. This invention provides methods and compositions for inducing pluripotency in differentiated mammalian cells. The methods involve mechanically aggregating the cells into discrete masses or embryoid-like bodies and treating them with a small molecule compound derived from programin, such as reversine. The second patent similarly focuses on the combinational use of mechanical manipulation and programin derivatives to enhance the expression of Oct4, Sox2, or Nanog in fibroblasts, further emphasizing the potential of these methods in regenerative medicine.

Career Highlights

Wai Yee Chan is affiliated with The Chinese University of Hong Kong, where she conducts her research and develops her innovative ideas. Her work has garnered attention in the scientific community, contributing to advancements in cellular biology and regenerative therapies.

Collaborations

Wai Yee Chan collaborates with esteemed colleagues, including Kenneth Ka Ho Lee and Tommy Lok Man Lo. These partnerships enhance her research efforts and foster a collaborative environment for innovation.

Conclusion

Wai Yee Chan's contributions to biotechnology through her patents and research at The Chinese University of Hong Kong highlight her role as a leading inventor in the field. Her innovative methods for inducing pluripotency in cells pave the way for future advancements in regenerative medicine.