Company Filing History:
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Years Active: 2012-2025
Title: W James Cook: Innovator in Neurodegenerative Disease Treatment
Introduction
W James Cook is a prominent inventor based in Hanover, NH (US), known for his significant contributions to the field of biotechnology. He holds a total of four patents, focusing on innovative solutions for treating neurodegenerative diseases and disorders. His work has the potential to transform therapeutic approaches in this critical area of healthcare.
Latest Patents
One of his latest patents is titled "Chimeric antigen receptors for treatment of neurodegenerative diseases and disorders." This patent relates to novel chimeric antigen receptors (CARs) and modified regulatory T cells (Tregs) that express these CARs. The invention aims to prevent oxidative and inflammatory activity while promoting neuronal growth and survival through the use of nerve growth factors and non-classical neurotrophic factors. The patent also discusses compositions containing these modified Tregs and their therapeutic applications for treating and preventing neurodegenerative diseases, particularly in individuals at risk due to genetic factors or those showing early signs of such diseases.
Another significant patent by W James Cook is "Production of glycoproteins with reduced O-glycosylation." This patent describes a method for producing protein compositions with reduced amounts of O-linked glycosylation. The method involves culturing cells in the presence of an inhibitor of Pmt-mediated O-linked glycosylation and/or one or more α-1,2-mannosidases, which can enhance the efficiency of glycoprotein production.
Career Highlights
Throughout his career, W James Cook has worked with notable companies such as Glycofi, Incorporated and Merck Sharp & Dohme Corporation. His experience in these organizations has contributed to his expertise in biotechnology and innovation in therapeutic development.
Collaborations
W James Cook has collaborated with esteemed colleagues, including Piotr Bobrowicz and Warren Charles Kett. These partnerships have further enriched his research and development efforts in the field of biotechnology.
Conclusion
W James Cook's innovative work in the realm of neurodegenerative disease treatment showcases his commitment to advancing medical science. His patents reflect a deep understanding of complex biological processes and a dedication to improving patient outcomes.