Vojo P Deretic

Title: Vojo P Deretic: Innovator in Autophagy Research

Introduction

Vojo P Deretic is a prominent inventor based in Placitas, NM (US), known for his significant contributions to the field of autophagy research. With a total of 13 patents to his name, Deretic has made remarkable strides in understanding the mechanisms of autophagy and its implications for various diseases.

Latest Patents

Among his latest patents, one notable invention is focused on the cooperation of TRIM proteins and galectins in influencing autophagy. This invention outlines compositions and methods that modulate TRIM proteins, particularly TRIM 8, TRIM 10, TRIM 16, TRIM 19, and TRIM 51, along with galectins, especially galectin 3. The goal is to treat diseases related to autophagy, including inflammatory diseases, microbial infections, neurodegenerative disorders, and cancer. Another significant patent involves the discovery that TBK1 phosphorylates Syntaxin 17, which is crucial for controlling autophagy initiation. This invention proposes the use of TBK1 inhibitors or Syntaxin 17 phosphorylation inhibitors in cancer treatment, aiming to reduce metastasis and recurrence in patients.

Career Highlights

Vojo P Deretic has had a distinguished career, contributing to various research initiatives and innovations. His work has been instrumental in advancing the understanding of autophagy and its therapeutic potential. He has been associated with institutions such as Stc.unm and UNM Rainforest Innovations, where he has collaborated on groundbreaking research.

Collaborations

Some of his notable coworkers include Graham Timmins and Eliseo F Castillo, who have contributed to his research endeavors.

Conclusion

Vojo P Deretic's innovative work in the field of autophagy has the potential to transform the treatment of various diseases. His patents reflect a deep understanding of complex biological processes and their implications for health.