The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

May. 10, 2012
Applicants:

Vojo Deretic, Placitas, NM (US);

Eliseo Castillo, Albuquerque, NM (US);

Steven Bradfute, Albuquerque, NM (US);

Larry A. Sklar, Albuquerque, NM (US);

Inventors:

Vojo Deretic, Placitas, NM (US);

Eliseo Castillo, Albuquerque, NM (US);

Steven Bradfute, Albuquerque, NM (US);

Larry A. Sklar, Albuquerque, NM (US);

Assignee:

STC.UNM, Albuquerque, NM (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/12 (2006.01); A61K 31/65 (2006.01); C07K 16/18 (2006.01); G01N 33/68 (2006.01); A61K 31/436 (2006.01); A61K 31/4365 (2006.01); A61K 31/4535 (2006.01); A61K 31/472 (2006.01); A61K 31/473 (2006.01); A61K 31/517 (2006.01); A61K 31/522 (2006.01); A61K 31/54 (2006.01); A61K 31/546 (2006.01); A61K 31/5685 (2006.01); A61K 31/585 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
A61K 31/65 (2013.01); A61K 31/436 (2013.01); A61K 31/4365 (2013.01); A61K 31/4535 (2013.01); A61K 31/472 (2013.01); A61K 31/473 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/522 (2013.01); A61K 31/54 (2013.01); A61K 31/546 (2013.01); A61K 31/5685 (2013.01); A61K 31/585 (2013.01); C07K 16/18 (2013.01); G01N 33/56972 (2013.01); G01N 33/6893 (2013.01); G01N 2333/9015 (2013.01);
Abstract

The invention provides methods of treating autophagy mediated diseases and disorders and related pharmaceutical compositions, diagnostics, screening techniques and kits. In one embodiment, the invention provides a method of determining whether a subject suffers from, or is at risk of developing, and autophagy mediated disease state and/or condition by evaluating LC3 levels.


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