Vladislav B Bergo

Title: Innovations of Vladislav B Bergo

Introduction

Vladislav B Bergo is a prominent inventor based in Boston, MA, known for his significant contributions to the field of protein analysis. With a total of 17 patents to his name, Bergo has made remarkable advancements in the development of assays and methods for proteomic screening.

Latest Patents

Among his latest patents, Bergo has developed bead-based assays for protein analysis. These assays measure protein biomarkers of proteolytic activity in biological systems. In one embodiment, the assay involves incubating a sample containing multiple fragments of a naturally occurring protein with a bead array and subsequently analyzing individual reactive sites of the bead array by mass spectrometry. Another notable patent is focused on global proteomic screening of random bead arrays using mass spectrometry imaging. This method utilizes photocleavable mass tags to code a protein library displayed on beads randomly arrayed in an array substrate. A library of probes can be mixed with the protein-bead array to query the array, allowing for rapid identification of all interactions resulting from this mixing.

Career Highlights

Throughout his career, Bergo has worked with several innovative companies, including Ambergen, Inc. and Adeptrix Corporation. His work has significantly impacted the field of proteomics, leading to advancements in how proteins are analyzed and understood.

Collaborations

Some of his notable coworkers include Kenneth J Rothschild and Mark J Lim, who have collaborated with Bergo on various projects and patents.

Conclusion

Vladislav B Bergo's contributions to protein analysis and proteomics through his innovative patents and collaborations highlight his importance in the scientific community. His work continues to influence advancements in the field, showcasing the impact of his inventions.