Company Filing History:
4 out of 9 
3 out of 3 
1 out of 6 Years Active: 2004-2018
Title: Innovations of Vladimir Andrei Koulchin
Introduction
Vladimir Andrei Koulchin is a notable inventor based in Portland, ME (US). He has made significant contributions to the field of biotechnology, particularly in the development of methods for extracting and purifying polysaccharide antigens from bacteria. With a total of 8 patents to his name, Koulchin's work has implications for rapid detection of bacterial infections in various samples.
Latest Patents
Koulchin's latest patents include innovative methods for extracting an essentially protein-free O-polysaccharide or carbohydrate antigen from bacteria. This invention involves coupling the antigen to an activated chromatographic column through a protein space molecule, which is first conjugated to the antigen. The prepared column is then utilized for the affinity purification of raw polyvalent antibodies, enabling the rapid detection of the corresponding bacterium or its antibody in human bodily fluids such as urine, sputum, and blood, as well as in environmental samples. Another significant patent discloses a cell wall C-polysaccharide antigen that contains minimal protein content, which has been purified prior to deproteinization. This invention also includes the development of polyvalent antibodies that are affinity purified using a chromatographic affinity matrix coupled with the purified antigen.
Career Highlights
Throughout his career, Koulchin has worked with several companies, including Alere Scarborough, Inc. and Chemogen, Inc. His experience in these organizations has contributed to his expertise in the field of biotechnology and patent development.
Collaborations
Koulchin has collaborated with notable individuals in his field, including Elena Valentin Molokova and Norman James Moore. These collaborations have likely enhanced his research and innovation efforts.
Conclusion
Vladimir Andrei Koulchin's contributions to biotechnology through his patents and collaborations highlight his role as a significant inventor in the field. His work continues to impact the methods used for bacterial detection and purification.