The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2018

Filed:

Aug. 18, 2015
Applicant:

Alere Scarborough, Inc., Scarborough, ME (US);

Inventors:

Vladimir A. Koulchin, Portland, ME (US);

Norman J. Moore, North Berwick, ME (US);

Elena V. Molokova, Portland, ME (US);

Assignee:

Alere Scarborough, Inc., Scarborough, ME (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 33/569 (2006.01); C07K 16/12 (2006.01); G01N 33/53 (2006.01); G01N 21/78 (2006.01); G01N 21/75 (2006.01); G01N 21/77 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56911 (2013.01); C07K 16/126 (2013.01); G01N 21/78 (2013.01); G01N 33/53 (2013.01); G01N 2021/752 (2013.01); G01N 2021/757 (2013.01); G01N 2021/7759 (2013.01); G01N 2400/10 (2013.01); G01N 2469/10 (2013.01);
Abstract

The present invention involves extracting frombacteria, particularlybacteria, an essentially protein-free O-polysaccharide or carbohydrate antigen, coupling this antigen to an activated chromatographic column through a protein space molecule which is first conjugated to the antigen, utilizing the column thus prepared for the affinity purification of raw polyvalent antibodies to the samebacterium from which the O-polysaccharide or carbohydrate antigen was separated—thereby obtaining antigen-specific antibodies which are useful for the rapid detection of the correspondingbacterium or its antibody in human bodily fluids such as urine, sputum, blood and the like or in environmental samples suspected of harboring thebacterium.


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