Virginie Sandrin

Title: Virginie Sandrin: Innovator in Viral Vector Technology

Introduction

Virginie Sandrin is a prominent inventor based in Lyons, France. She has made significant contributions to the field of viral vector technology, particularly in the development of chimeric glycoproteins and pseudotyped lentiviral vectors. Her work has implications for gene transfer applications, enhancing the efficiency and effectiveness of viral vectors.

Latest Patents

Virginie Sandrin holds 2 patents related to her innovative work. Her latest patents focus on methods for producing recombinant pseudotyped viral vector particles. One method involves transfecting a cell with various constructs to yield a producer cell, which is then cultured to recover the recombinant viral vector particle. This approach results in significantly higher titers compared to vectors coated with non-chimeric glycoproteins. Additionally, her inventions provide improved chimeric glycoproteins and lentiviral vectors, which are essential for in vitro and in vivo transduction of cells.

Career Highlights

Throughout her career, Virginie Sandrin has worked with esteemed institutions such as the National Institute of Health and Medical Research (Institut National De La Sante Et De La Recherche Medicale) and the Clayton Institute for Research (Institut Clayton De La Recherche). Her research has been pivotal in advancing the understanding and application of viral vectors in gene therapy.

Collaborations

Virginie has collaborated with notable scientists in her field, including Didier Trono and Francois-Loic Cosset. These collaborations have further enriched her research and contributed to the advancements in viral vector technology.

Conclusion

Virginie Sandrin's innovative work in the field of viral vectors has positioned her as a leading inventor in biotechnology. Her contributions continue to influence gene transfer applications and enhance the effectiveness of therapeutic interventions.